Is Spicy Tuna Roll Gluten Free?
A traditional spicy tuna roll is typically not gluten-free due to the soy sauce used in the spicy mayo mixture and the presence of wheat in most soy sauces. However, it’s possible to make a gluten-free version by using gluten-free soy sauce and ensuring all other ingredients are free from gluten contamination.

High in protein: Tuna is an excellent source of lean protein, which is essential for muscle growth and repair.
Rich in omega-3 fatty acids: Tuna contains omega-3s, which are beneficial for heart health and may reduce inflammation.
Good source of vitamins: Tuna provides vitamins B6 and B12, which are important for brain function and energy metabolism.
Contains selenium: Tuna is high in selenium, an antioxidant that supports thyroid function and immune health.
Low in calories: When prepared traditionally, spicy tuna rolls are relatively low in calories compared to other sushi rolls.
Provides iodine: Seaweed used in sushi rolls contains iodine, which is crucial for thyroid function.
May boost metabolism: The spicy component (often from sriracha or chili oil) can temporarily increase metabolism.
Contains niacin: Tuna is a good source of niacin, which helps with digestion and nervous system function.
Offers mineral content: Tuna provides minerals like magnesium and potassium, important for various bodily functions.Remember that the health benefits can vary based on preparation methods and additional ingredients used in the roll.
Pregnant women: Due to the risk of foodborne illness from raw fish
Young children: Their immune systems may not be fully developed to handle raw fish
Elderly individuals: They may have weakened immune systems
People with compromised immune systems: Including those undergoing chemotherapy or with HIV/AIDS
Individuals with seafood allergies: Especially those allergic to tuna or other fish
People with shellfish allergies: As cross-contamination can occur in sushi preparation areas
Those with a low tolerance for spicy foods: The “spicy” component may cause discomfort
Individuals taking blood thinners: Due to potential interactions with high levels of Vitamin K in seaweed
People with gout: As some fish are high in purines
Those with high mercury concerns: Tuna can contain higher levels of mercury compared to other fish
Individuals with gastrointestinal sensitivities: Raw fish may be harder to digest
People following specific religious dietary laws: Some religions prohibit the consumption of raw fishRemember that these are general guidelines, and it’s always best to consult with a healthcare professional for personalized advice.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently Asked Questions
Our Expert
Drs. Ilse van Asperen
Drs. Ilse van Asperen is a medical doctor specialising in orthomolecular therapy and nutritional coaching. With a background in public and clinical health research and management, she focuses on addressing the root causes of health issues through diet, gut health, and stress reduction. As a professional editor for Little Helpers, she reviews all gluten-free content to ensure accuracy, safety, and scientific credibility. More about me
Our Sources
The information on this page is based on reputable health and nutrition organisations, ensuring accuracy and reliability for anyone following a gluten-free diet. For further details, see the sources below.
Sources
Experiences of our customers
Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.