Is Spinach Gluten Free?
Yes, spinach is naturally gluten-free. As a leafy green vegetable, spinach does not contain any gluten proteins, which are typically found in wheat, barley, and rye.

High in nutrients and low in calories
Rich in antioxidants, including vitamin C, lutein, and zeaxanthin
Excellent source of vitamin K, important for bone health
Contains iron, which helps prevent anemia and supports oxygen transport
Good source of folate, essential for DNA synthesis and cell division
Provides nitrates, which may help lower blood pressure
Contains quercetin, which may reduce inflammation and prevent infections
Rich in fiber, promoting digestive health and regularity
May help with weight management due to low calorie content
Contains kaempferol, which may reduce the risk of cancer
Supports eye health due to high levels of lutein and zeaxanthin
Provides magnesium, which is important for energy production and muscle function
Contains potassium, which helps maintain healthy blood pressure levels
May help regulate blood sugar levels due to its high antioxidant content
Supports brain health and may slow cognitive decline
Promotes healthy skin and hair due to its vitamin A contentRemember that while spinach is highly nutritious, it’s important to consume it as part of a balanced diet for optimal health benefits.
People taking blood thinners (e.g., warfarin): Spinach is high in vitamin K, which can interfere with these medications.
Individuals with kidney stones or a history of kidney stones: Spinach is high in oxalates, which can contribute to kidney stone formation.
Those with gout or at risk for gout: Spinach contains purines, which can increase uric acid levels.
People with iron overload disorders (e.g., hemochromatosis): Spinach contains iron, which could exacerbate their condition.
Individuals with thyroid issues: Spinach contains goitrogens, which can interfere with thyroid function in large amounts.
Those with a known allergy or sensitivity to spinach.
People taking certain medications that interact with vitamin K (consult with a healthcare provider).
Individuals with calcium oxalate stones: Spinach’s high oxalate content may be problematic.
Those on a low-potassium diet: Spinach is high in potassium, which may be an issue for some people with kidney problems.
Infants under 4 months old: Spinach contains nitrates, which can be harmful to very young babies.It’s always best to consult with a healthcare professional for personalized advice regarding diet and nutrition.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently
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Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.