Is Spirulina Gluten Free?
Yes, spirulina is naturally gluten-free. As a type of blue-green algae, spirulina does not contain any wheat, barley, rye, or other gluten-containing grains.

Highly nutritious: Rich in protein, vitamins, minerals, and antioxidants
Powerful antioxidant properties: Contains phycocyanin, which combats free radicals
May lower “bad” LDL cholesterol and triglycerides
Potential anti-cancer properties, particularly against oral cancer
May reduce blood pressure
Improves symptoms of allergic rhinitis
May help control blood sugar levels
Enhances endurance and muscle strength
Potential anti-inflammatory effects
May help with anemia, especially in older adults
Boosts immune system function
Potential neuroprotective properties, may benefit brain health
May aid in weight loss by reducing appetite
Supports gut health by promoting the growth of beneficial bacteria
Possible detoxification properties, particularly for heavy metals
May improve symptoms of ADHD in some individuals
Potential anti-viral properties
Could help alleviate PMS symptoms
May enhance skin health and appearance
People with autoimmune disorders (e.g., lupus, multiple sclerosis, rheumatoid arthritis)
Individuals with phenylketonuria (PKU)
Those with seafood or iodine allergies
People taking blood-thinning medications (e.g., warfarin)
Pregnant women and breastfeeding mothers (due to limited research on safety)
Individuals with bleeding disorders
People with diabetes (as it may affect blood sugar levels)
Those with gout or at high risk for gout
Individuals with liver disease
People taking immunosuppressant drugs
Those with hyperthyroidism or other thyroid disorders
Individuals with a history of kidney stones
People sensitive to caffeine (Spirulina contains a small amount)
Children (unless under medical supervision)
Anyone scheduled for surgery within two weeksAlways consult with a healthcare professional before adding Spirulina or any new supplement to your diet, especially if you have pre-existing health conditions or are taking medications.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently
Asked Questions 1
Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.