Is Tomato Sauce Gluten Free?
Generally, pure tomato sauce is gluten-free as it’s made from tomatoes, which do not contain gluten. However, some commercially prepared tomato sauces may contain gluten-containing additives or be processed in facilities that handle gluten, so it’s always best to check the label or contact the manufacturer if you have celiac disease or gluten sensitivity.

Rich in lycopene, a powerful antioxidant that may reduce the risk of certain cancers
Good source of vitamins A and C, which support immune function and skin health
Contains potassium, which helps regulate blood pressure and supports heart health
Provides dietary fiber, aiding in digestion and promoting feelings of fullness
Low in calories, making it a good option for weight management
Contains vitamin K, which is important for bone health and blood clotting
Offers small amounts of iron, important for red blood cell production
May help reduce inflammation in the body due to its antioxidant content
Can contribute to better eye health due to its vitamin A and lycopene content
Potentially lowers the risk of heart disease when consumed as part of a balanced diet
May help protect skin from sun damage due to its lycopene content
Contains small amounts of vitamin E, which supports immune function and skin health
Cooking tomatoes (as in sauce) can increase the bioavailability of certain nutrientsRemember that the health benefits can vary depending on the specific recipe and any added ingredients in the tomato sauce.
Individuals with gastroesophageal reflux disease (GERD) or acid reflux, as tomatoes are acidic and can trigger symptoms
People with irritable bowel syndrome (IBS), especially those sensitive to FODMAPs
Those with tomato allergies or sensitivities
Individuals prone to kidney stones, as tomatoes are high in oxalates
People with arthritis or other inflammatory conditions, as nightshade vegetables like tomatoes may exacerbate symptoms in some cases
Those on a low-potassium diet due to kidney disease or certain medications
Individuals with histamine intolerance, as tomatoes are high in histamines
People with eczema or other skin conditions that may be triggered by nightshade vegetables
Those following a strict low-carb or ketogenic diet, as tomato sauce contains some carbohydrates
Individuals with citrus fruit allergies, as they may also react to tomatoes
People taking certain medications that interact with high-lycopene foods (consult with a healthcare provider)Remember that these are general guidelines, and individual tolerances may vary. Always consult with a healthcare professional for personalized advice.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

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Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.