Is Tuna Fish Gluten Free?
Yes, plain tuna fish is naturally gluten-free as it is simply fish and does not contain any wheat, barley, rye, or other gluten-containing grains. However, it’s important to check labels on canned or packaged tuna products, as some may contain additives or flavorings that could potentially include gluten.

High in protein: Tuna is an excellent source of lean protein, essential for muscle growth and repair.
Rich in omega-3 fatty acids: These healthy fats support heart health, reduce inflammation, and promote brain function.
Low in calories: Tuna is a low-calorie food, making it beneficial for weight management.
Contains essential vitamins: Tuna is a good source of vitamins B6 and B12, which support energy metabolism and nervous system function.
Provides minerals: It contains selenium, magnesium, and potassium, which are important for various bodily functions.
May lower blood pressure: The omega-3s in tuna can help reduce blood pressure.
Boosts immune system: Tuna contains zinc, which helps support immune function.
Supports eye health: The omega-3s in tuna may help prevent age-related macular degeneration.
May reduce the risk of certain cancers: Some studies suggest that consuming fish like tuna may lower the risk of certain types of cancer.
Helps in thyroid function: Tuna is a good source of iodine, which is essential for proper thyroid function.
Supports bone health: The vitamin D content in tuna contributes to maintaining strong bones.Remember to consume tuna in moderation due to potential mercury content, especially for pregnant women and young children.
Pregnant women: Due to the risk of mercury exposure, which can harm fetal development.
Breastfeeding mothers: Mercury can pass through breast milk to infants.
Young children: Their developing nervous systems are more susceptible to mercury’s effects.
People with mercury allergies or sensitivities.
Individuals with a fish or shellfish allergy: While rare, some people may be allergic to tuna.
Those with gout or at high risk for gout: Tuna is high in purines, which can trigger gout attacks.
People with kidney problems: High protein content in tuna may stress the kidneys.
Individuals taking MAO inhibitors: Tuna contains high levels of histamine, which can interact with these medications.
Those with cardiovascular concerns: Some types of tuna are high in sodium and cholesterol.
People with compromised immune systems: Raw or undercooked tuna may pose a risk of foodborne illness.
Individuals on a low-sodium diet: Canned tuna often contains added salt.Remember, it’s always best to consult with a healthcare professional for personalized dietary advice.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
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Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

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Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.