Vitamin E itself is naturally gluten-free. However, some vitamin E supplements may contain gluten-derived ingredients or be processed in facilities that also handle gluten-containing products, so it’s important to check the label or contact the manufacturer to ensure a specific supplement is gluten-free if you have celiac disease or gluten sensitivity.

Antioxidant properties: Protects cells from damage caused by free radicals
Immune system support: Enhances the body’s immune response
Skin health: Promotes healthy skin and may help reduce signs of aging
Eye health: May help prevent age-related macular degeneration
Heart health: May help reduce the risk of heart disease
Brain function: Supports cognitive health and may slow cognitive decline in older adults
Blood vessel health: Helps maintain healthy blood vessels
Reduced inflammation: May help reduce inflammation in the body
Cancer prevention: Some studies suggest it may help lower the risk of certain cancers
Liver support: May help protect the liver from damage
Hormone balance: Plays a role in the production and balance of hormones
Muscle health: Supports muscle strength and recovery
Reproductive health: Important for reproductive function in both males and females
Wound healing: May help promote faster wound healing
Blood clot prevention: May help prevent excessive blood clottingRemember that while Vitamin E offers these potential benefits, it’s important to consume it as part of a balanced diet and consult with a healthcare professional before taking supplements.
People taking blood-thinning medications (e.g., warfarin, heparin) as Vitamin E may increase the risk of bleeding
Individuals with bleeding disorders, such as hemophilia or von Willebrand disease
Those scheduled for surgery, as Vitamin E can increase bleeding risk during and after the procedure
People with a history of hemorrhagic stroke
Individuals with vitamin K deficiency
Those with retinitis pigmentosa, as high doses of Vitamin E may worsen the condition
People with heart failure, especially those taking diuretics
Individuals with head and neck cancer who are undergoing radiation therapy
Those with a history of prostate cancer, as some studies suggest high Vitamin E intake may increase risk
Premature infants, due to the risk of potentially life-threatening complications
People taking certain chemotherapy drugs, as Vitamin E may interfere with treatment effectiveness
Individuals with liver disease or impaired liver function
Those with allergies to Vitamin E or any ingredients in Vitamin E supplementsAlways consult with a healthcare professional before starting or stopping any supplement regimen, especially if you have pre-existing health conditions or are taking medications.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

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