Is Watermelon Gluten Free?
Yes, watermelon is naturally gluten-free. As a fruit, it does not contain any wheat, barley, rye, or other gluten-containing grains.

High in antioxidants, particularly lycopene
Good source of vitamin C and vitamin A
Contains citrulline, which may improve exercise performance
Low in calories and high in water content, aiding hydration
May help reduce inflammation and oxidative stress
Potentially lowers blood pressure and improves heart health
Contains compounds that may have anti-cancer effects
May help relieve muscle soreness
Good for skin health due to vitamin A and C content
Supports eye health with its beta-carotene and vitamin C
May aid in weight loss due to its low calorie and high water content
Contains potassium, which is beneficial for heart and muscle function
May help prevent kidney stones
Supports digestive health due to its water and fiber content
Potentially improves insulin sensitivity in some individualsRemember, while watermelon has many potential health benefits, it should be consumed as part of a balanced diet for optimal health.
Individuals with diabetes or high blood sugar levels, due to watermelon’s high glycemic index
People with kidney problems, as watermelon is high in potassium which can be harmful in large amounts for those with kidney issues
Those with allergies to watermelon or other members of the Cucurbitaceae family (such as cucumbers, pumpkins, or squash)
Individuals taking certain medications that interact with lycopene (found in watermelon), such as blood thinners
People with irritable bowel syndrome (IBS) or other digestive issues, as watermelon can cause bloating and gas in some individuals
Those following a low-FODMAP diet, as watermelon is high in fructose
Individuals prone to migraines, as tyramine in watermelon may trigger headaches in some people
People with latex allergies, due to potential cross-reactivity
Those with a condition called glucose-6-phosphate dehydrogenase deficiency, as large amounts of watermelon may cause hemolytic anemia
Individuals on a low-carb or ketogenic diet, due to watermelon’s high carbohydrate contentRemember, it’s always best to consult with a healthcare professional for personalized advice regarding dietary restrictions or concerns.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

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Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.