Is Wheat Bran Gluten Free?
Wheat bran itself does not contain gluten, as gluten is found in the endosperm of wheat, not the bran. However, wheat bran is often processed in facilities that also handle gluten-containing grains, so there’s a risk of cross-contamination, meaning it may not be suitable for those with celiac disease or severe gluten sensitivity unless specifically labeled as gluten-free.

High in dietary fiber, promoting digestive health and regularity
Helps lower cholesterol levels, particularly LDL (bad) cholesterol
Aids in weight management by increasing feelings of fullness
Regulates blood sugar levels, beneficial for diabetes management
Rich in antioxidants, which may help protect against certain diseases
Contains essential minerals like magnesium, zinc, and iron
Supports colon health and may reduce the risk of colon cancer
Helps prevent diverticular disease
Provides a good source of B vitamins, including folate and niacin
May reduce the risk of heart disease due to its fiber content
Supports the growth of beneficial gut bacteria
Can help alleviate constipation and improve overall bowel function
May reduce the risk of gallstones and kidney stones
Contains phytochemicals that may have anti-inflammatory properties
Supports healthy skin due to its vitamin and mineral contentRemember that while wheat bran offers many benefits, it’s important to introduce it gradually into your diet and drink plenty of water to avoid digestive discomfort.
People with celiac disease: Wheat bran contains gluten, which can trigger severe reactions in those with celiac disease.
Individuals with non-celiac gluten sensitivity: They may experience discomfort or other symptoms when consuming wheat products, including bran.
Those with wheat allergies: Wheat bran can cause allergic reactions in people with wheat allergies.
Individuals with irritable bowel syndrome (IBS): Some people with IBS may find that wheat bran exacerbates their symptoms.
People with inflammatory bowel diseases: Those with conditions like Crohn’s disease or ulcerative colitis may need to limit fiber intake, including wheat bran, during flare-ups.
Individuals recovering from certain gastrointestinal surgeries: They may need to avoid high-fiber foods like wheat bran temporarily.
People on low-fiber diets: For medical reasons, some individuals may need to restrict their fiber intake.
Those taking certain medications: Wheat bran can interfere with the absorption of some medications, so it’s important to consult with a healthcare provider.
Individuals with diverticulitis: During acute flare-ups, a low-fiber diet may be recommended.Always consult with a healthcare professional before making significant changes to your diet, especially if you have existing health conditions.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

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Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.