Wheat dextrose is generally considered gluten-free, as the process of creating dextrose from wheat starch removes the gluten protein. However, individuals with severe gluten sensitivities or celiac disease should still exercise caution and consult with their healthcare provider, as there may be a very small risk of trace gluten contamination depending on the manufacturing process.

Quick energy source: As a simple sugar, it provides rapid energy for the body, which can be beneficial during physical activities or for individuals with low blood sugar.
Easily digestible: The body can quickly absorb and utilize wheat dextrose, making it a good option for those with digestive issues or athletes needing fast-acting carbohydrates.
Hydration aid: When combined with electrolytes, it can help improve fluid absorption, making it useful in oral rehydration solutions.
Post-workout recovery: It can help replenish glycogen stores in muscles after intense exercise.
Medical applications: Used in intravenous solutions to treat dehydration, shock, and low blood sugar levels in clinical settings.
Prebiotic potential: Some studies suggest it may have prebiotic properties, potentially supporting gut health.
Alternative for fructose intolerance: It can be used as a sweetener for individuals who cannot tolerate fructose.
Flavor enhancer: In food products, it can improve taste and texture without adding significant calories.It’s important to note that while these benefits exist, wheat dextrose should be consumed in moderation as part of a balanced diet, especially for individuals managing their blood sugar levels or weight.
People with celiac disease: – Wheat dextrose is derived from wheat and may contain gluten
Individuals with non-celiac gluten sensitivity: – May experience adverse reactions to gluten-containing products
Those with wheat allergies: – Wheat dextrose is derived from wheat and can trigger allergic reactions
People following a gluten-free diet: – For medical reasons or personal choice
Individuals with diabetes: – Should monitor their intake of dextrose, as it can affect blood sugar levels
Those with fructose malabsorption: – May have difficulty processing dextrose
People with irritable bowel syndrome (IBS): – Some may experience digestive issues with wheat-based products
Individuals following a low FODMAP diet: – Wheat-based products are typically restricted on this diet
Those with inflammatory bowel diseases (IBD): – Such as Crohn’s disease or ulcerative colitis, who may be sensitive to wheat products
People trying to reduce their intake of refined carbohydrates: – Dextrose is a simple sugar and may not align with their dietary goalsIt’s important to note that the severity of reactions can vary among individuals, and anyone with concerns should consult a healthcare professional or registered dietitian for personalized advice.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

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