Whole grain is not inherently gluten-free, as many whole grains (such as wheat, barley, and rye) contain gluten. However, there are gluten-free whole grains available, such as quinoa, brown rice, and oats (when certified gluten-free), which can be consumed by those following a gluten-free diet.
Rich in fiber, which aids digestion and promotes feelings of fullness
May help lower cholesterol levels, reducing the risk of heart disease
Can help regulate blood sugar levels, beneficial for diabetes management
Contain more vitamins and minerals than refined grains
May reduce the risk of certain types of cancer, particularly colorectal cancer
Can assist in weight management due to their filling nature
Provide a good source of complex carbohydrates for sustained energy
Contain antioxidants that help protect cells from damage
May reduce inflammation in the body
Support gut health by promoting beneficial gut bacteria
Can help lower blood pressure
May reduce the risk of stroke
Provide essential nutrients like B vitamins, iron, magnesium, and selenium
Can contribute to better bone health due to mineral content
May improve cognitive function and reduce the risk of cognitive decline
Support a healthy immune systemRemember that these benefits are most pronounced when whole grains are consumed as part of a balanced, healthy diet.
People with celiac disease: They must avoid all grains containing gluten, including whole wheat, barley, and rye.
Individuals with non-celiac gluten sensitivity: They may experience adverse reactions to gluten-containing whole grains.
Those with wheat allergies: They should avoid wheat-based whole grain products.
People with certain digestive disorders: Conditions like irritable bowel syndrome (IBS) or inflammatory bowel disease (IBD) may be aggravated by high-fiber whole grains.
Individuals on a low FODMAP diet: Some whole grains are high in FODMAPs, which can cause digestive issues for sensitive people.
Those with diverticulitis: During acute flare-ups, a low-fiber diet is often recommended.
People on a ketogenic or very low-carb diet: Whole grains are typically too high in carbohydrates for these diets.
Individuals with grain allergies: Some people may be allergic to specific grains.
Those with certain autoimmune conditions: Some autoimmune protocols suggest avoiding grains.
People with difficulty digesting phytic acid: Whole grains contain phytic acid, which can interfere with mineral absorption in sensitive individuals.Always consult with a healthcare professional or registered dietitian before making significant changes to your diet, especially if you have health concerns or dietary restrictions.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.
What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills
Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.
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