No, whole wheat is not gluten-free. Whole wheat contains gluten, which is a protein found in wheat, barley, and rye.

Rich in fiber, which aids digestion and promotes feelings of fullness
Contains more nutrients than refined wheat, including B vitamins, iron, zinc, magnesium, and vitamin E
May help lower the risk of heart disease
Can assist in weight management due to its high fiber content
Helps regulate blood sugar levels, potentially reducing the risk of type 2 diabetes
Contains antioxidants that may help protect against certain cancers
Supports gut health by promoting the growth of beneficial bacteria
May reduce chronic inflammation in the body
Provides a good source of plant-based protein
Can help lower cholesterol levels
May reduce the risk of stroke
Supports healthy bowel movements and prevents constipation
Contains phytochemicals that may have various health-promoting effects
Provides sustained energy due to its complex carbohydratesRemember that while whole wheat offers many benefits, it’s important to consume it as part of a balanced diet and to be aware of any personal sensitivities or allergies to wheat products.
People with celiac disease: Whole wheat contains gluten, which can trigger severe autoimmune reactions in those with celiac disease.
Individuals with non-celiac gluten sensitivity: Some people experience adverse reactions to gluten without having celiac disease.
Those with wheat allergies: People allergic to wheat proteins should avoid all wheat products, including whole wheat.
Individuals with irritable bowel syndrome (IBS): Some people with IBS may find that wheat exacerbates their symptoms.
People following a low FODMAP diet: Whole wheat contains FODMAPs, which can cause digestive issues in sensitive individuals.
Those with inflammatory bowel diseases: Some people with Crohn’s disease or ulcerative colitis may need to limit or avoid whole wheat.
Individuals on a ketogenic or very low-carb diet: Whole wheat is high in carbohydrates and may not fit into these dietary plans.
People with certain autoimmune conditions: Some individuals with autoimmune disorders may benefit from avoiding gluten-containing grains like wheat.
Those with wheat intolerance: Some people may have difficulty digesting wheat without having celiac disease or a wheat allergy.
Individuals following a paleo or grain-free diet: These diets typically exclude all grains, including whole wheat.Always consult with a healthcare professional or registered dietitian before making significant changes to your diet, especially if you have underlying health conditions.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

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