Wine yeast is typically gluten-free as it is derived from strains of Saccharomyces cerevisiae, which do not contain gluten. However, it’s always best to check with the specific manufacturer or brand, as some yeasts may be processed in facilities that also handle gluten-containing products, potentially leading to cross-contamination.

Rich in B-complex vitamins: Wine yeast is a good source of various B vitamins, including B1, B2, B3, B5, B6, and B9 (folate).
Contains minerals: It provides essential minerals such as selenium, chromium, zinc, and magnesium.
High in protein: Wine yeast is a complete protein source, containing all essential amino acids.
Beta-glucans: These compounds found in yeast cell walls may help boost the immune system.
Antioxidant properties: Some components in wine yeast may have antioxidant effects, potentially protecting cells from damage.
Digestive health: As a probiotic, it may support gut health and aid digestion.
Potential cholesterol-lowering effects: Some studies suggest yeast may help reduce LDL (bad) cholesterol levels.
Blood sugar regulation: Chromium in yeast may help improve insulin sensitivity and blood sugar control.
Skin health: B vitamins and minerals in yeast may contribute to healthier skin.
Energy boost: The B vitamins in yeast play a crucial role in energy metabolism.It’s important to note that while these potential benefits exist, more research is needed to fully understand the health impacts of wine yeast consumption. Always consult with a healthcare professional before adding any new supplement to your diet.
People with yeast allergies or sensitivities
Individuals with Candida overgrowth or yeast infections
Those following a low-carb or ketogenic diet, as yeast can contain carbohydrates
People with certain autoimmune conditions that may be aggravated by yeast
Individuals with compromised immune systems, as they may be more susceptible to yeast-related issues
Those with inflammatory bowel diseases, such as Crohn’s disease or ulcerative colitis
People following a strict vegan diet, as some wine yeasts may be cultured on animal-derived nutrients
Individuals with severe alcohol intolerance or alcohol-related health issues
Those taking certain medications that may interact with yeast or its byproducts
People with specific religious or cultural restrictions on consuming yeast or fermented products
Pregnant women, as a precautionary measure (though small amounts are generally considered safe)
Young children, due to their developing immune systems and potential sensitivitiesNote that for most healthy adults, wine yeast in moderate amounts is generally considered safe. However, it’s always best to consult with a healthcare professional if you have concerns about consuming wine yeast.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently
Asked Questions 1
Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.