Is Yeast Gluten Free?
Yeast itself is naturally gluten-free. However, some products containing yeast may also contain gluten, so it’s important for people with celiac disease or gluten sensitivity to check product labels carefully.

Nutritional value: It’s a good source of B-complex vitamins, proteins, and minerals.
Probiotic properties: Some types of yeast, like Saccharomyces boulardii, can act as probiotics, supporting gut health.
Vitamin production: Yeast can be used to produce vitamin supplements, particularly B vitamins which helps your body maintain healthy metabolism.
The fiber in nutritional yeast, beta-glucan, may reduce cholesterol levels.
Nutritional yeast is also a low-glycemic food that contains chromium which helps regulate blood sugar.
Nutritional yeast may improve your physical recovery after exercising.
People with yeast allergies or sensitivities
Those with inflammatory bowel diseases (IBD) like Crohn’s disease or ulcerative colitis
Individuals with candida overgrowth or recurring yeast infections
People following a low-FODMAP diet for digestive issues
Those with autoimmune conditions that may be aggravated by yeast
Individuals with compromised immune systems
People with certain genetic disorders that affect their ability to break down purines (e.g., gout)
Those on a prescribed anti-candida diet
Individuals taking certain medications that may interact with nutritional yeast (e.g., MAO inhibitors)
People with chronic migraines that may be triggered by high-tyramine foods
Those following specific diets that exclude yeast (e.g., some versions of the Paleo diet)Note that in many cases, consumption of yeast may be acceptable under medical supervision or in moderation. Always consult with a healthcare professional for personalized advice.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently
Asked Questions 1
Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.